12:00-17:00

Registration

12:30-15:30

Council of Physiology Professors     [Aula E]

13:30-15:30

Young Physiologists Roundtable     [Aula Magna]

Vaida Bankauskaite, MD Ph.D. (LS4 panel Coordinator at the European Research Council Executive Agency)

ERC funding opportunities for young physiologists

Luis Monteiro Rodrigues (EURAP Coordinator at FEPS)

Building a new European identity in Physiology: the EURAP initiative

13:30-15:30

FEPS Council     [Aula S]

15:30-16:00

Opening Ceremony     [Aula Magna]

16:00-17:00

Opening Lecture     [Aula Magna]

Susan Wray (Liverpool, United Kingdom)

The Science and Future of the Uterus

17:30-18:30

Welcome cocktail     [Chiostro di San Faustino]

19:00-20:00

Piano Concert      [Chiesa di San Giuseppe]

08:30-10:00

Parallel Symposia

Special event on the occasion of the 150th anniversary of the Physiological Society
Building on the breakthroughs of Dr Florence Buchanan: advancing the frontiers of muscle physiology (Sponsored by The Physiological Society)     [Aula Magna]
Chairs: Damian Bailey (Cardiff, United Kingdom) & Sarah Bundock (London, United Kingdom)

Damian Bailey (Cardiff, United Kingdom)

From Reflex Arcs to Missing Faces: the Science and Legacy of Dr Florence Buchanan

Colleen Deane (Southampton, United Kingdom)

Muscle Health Across the Lifecourse: Nutrition, Exercise and the Utility of Omics

Jakob Škarabot (Loughborough, United Kingdom)

The Neural-Contractile Nexus in Healthy Ageing

Grith Stougaard Højfeldt (Copenhagen, Denmark)

Regulation of Human Skeletal Muscle Following Injury: Dual-Omics and Protein Turnover Insights

Neurocardiac cross-talk in inherited and acquired cardiac disease     [Auditorium A1]
Chairs: Molly O'Reilly (Amsterdam, The Netherlands) & Jolanda van der Velden (Amsterdam, The Netherlands)

Tania Zaglia (Padua, Italy)

Altered Sympathetic Innervation and Protective Effects of Denervation in Arrhythmogenic Cardiomyopathy

Bastiaan Boukens (Maastricht, The Netherlands)

TBA

Molly O'Reilly (Amsterdam, The Netherlands)

Redefining Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) as a Neurocardiac Condition

Christopher O’Shea (Birmingham, United Kingdom)

TBA

Understanding how complex cognition transforms sensory information: neural computations from single neurons to cell assembly in the frontal cortex     [Auditorium B1]
Chairs: Francesco Ceccarelli (Rome, Italy) & Aldo Genovesio (Novara, Italy)

Emiliano Brunamonti (Rome, Italy)

Neural Computations Underlying Decision-Making Supported by Mental Schemas

Aldo Genovesio (Novara, Italy)

Reviving Hebb’S Theory: From Single Neurons to Neuronal Assemblies as Units of Information Processing

Surabhi Ramawat (Lyon, France)

Learning to Choose by Rank-Order: Reconfiguration of Stimulus Encoding in Primate Prefrontal Cortex after Learning During a Transitive Inference Task

Sofia Raglio (Paris, France)

From Sequence Processing to Abstract Cognition: Transitive Inference Paradigm in Artificial and Cortical Networks

How the retina computes: circuit motifs, state modulation, and timing strategies for the brain     [Auditorium C1]
Chairs: Stefano Di Marco (Genoa, Italy) & Serena Riccitelli (Genoa, Italy)

Olivier Marre (Paris, France)

VIP+ Amacrine Cells Synchronize Retinal Activity

Michal Rivlin (Rehovot, Israel)

Direction Selectivity and Its Role in Encoding Visual Cues to Self-Motion: from the Retina to the Visual Thalamus

Serena Riccitelli (Genoa, Italy)

Top-Down Modulation of the Retinal Code via Histaminergic Neurons of the Hypothalamus

Annalisa Bucci (Basel, Switzerland)

Synchronization of Visual Signals in the Human Fovea: Insights from Electrophysiological Recordings and Beyond

10:00-11:00

Parallel Oral Communications

Synaptic Physiology and Mechanisms of Neural Plasticity     [Aula Magna]

Natalia Abate (Naples, Italy)

Involvement of Serotonin Receptor 7 in Autism Spectrum Disorder Synaptic Dysfunctions

Giuseppe Aceto (Rome, Italy)

Reduced Metabotropic Glycine Receptor Expression in the Nucleus Accumbens Contributes to Synaptic Dysfunction in Stress-Susceptible Mice

Claudia Colussi (Rome, Italy)

HDAC4-Dependent SUMO2/3-ylation of Synapsin I Defines a Novel Regulatory Mechanism of Synaptic Function

Maria Rosaria Tropea (Catania, Italy)

α7 Nicotinic Acetylcholine Receptors Are Required for NO–cGMP-Dependent Synaptic Plasticity and Memory

Cardiac Cellular Physiology, Metabolism and Stress Adaptation     [Auditorium A1]

Masaba Baroi (Bern, Switzerland)

Impact of Substrate Stiffness on Mechanosensitive Signaling and Electrical Adaptation in hiPSC-CM

Iveta Bernatova (Bratislava, Slovakia)

Genotype-Specific Effects of Dimethyl Fumarate on Cardiometabolic Profile and Vascular Reactivity in Normotensive and Hypertriglyceridemic Rats

Chiara Coppola (Lecce, Italy)

miR-21-5p Regulates Mitochondrial Adaptation and Metabolic Remodeling in AC16 Cardiomyocytes

Magalì Giordano (Orbassano, TO, Italy)

GRIN2A Mutation Enhances Susceptibility to Myocardial Ischemia-Reperfusion Injury: Association with NLRP3 Activation and Sex Differences

Cellular and Synaptic Mechanisms in Alzheimer's Disease     [Auditorium B1]

Beatrice Cannata (Rome, Italy)

Lithiated Gold Nanoparticles as a Promising Therapeutic Ttrategy for Alzheimer's Disease Treatment

Salvatore Fusco (Rome, Italy)

Antisense Oligonucleotide-Based Intranasal Treatment Targeting zDHHC7 Enzyme as New Therapeutic Strategy Ameliorating Synaptic and Cognitive Deficits in Alzheimer's Disease

Francesca Natale (Rome, Italy)

Role of zDHHC-Driven Aberrant Palmitoylation in High Fat Diet- and Alzheimer’S Disease-Related Alteration of Hippocampal Dendritic Spine Density

Ida Nifo Sarrapochiello (Rome, Italy)

Intranasal Administration of Stem Cell-Derived Extracellular Vesicles Mitigates Ad-Related Cognitive Decline by Reducing Neuroinflammation and Inhibiting Aβ Deposition

Mitochondrial Metabolism and Lipid Homeostasis     [Auditorium C1]

Antonia Giacco (Benevento, Italy)

A Mitochondria-Centred Approach to MASLD: 3,5-Diiodo-L-Thyronine and TAT-Beclin1 Side by Side

Mayra Colardo (Pesche, IS, Italy)

Branched-Chain Amino Acids and Di-Alanine Attenuate Skeletal Muscle Wasting in a Murine Model of Cancer Cachexia

Anna Palmiero (Naples, Italy)

Mitochondrial Fatty Acid Overload Drives DRP1-Dependent Lipid Trapping in Hypertrophic Adipocytes

Michela Terlizzi (Fisciano, SA, Italy)

Ceramidase Is Involved in Metabolic Reprogramming of Fibroblasts During Hypoxia Conditions

11:00-11:30

Coffee break

11:30-12:30

FEPS Lecture     [Aula Magna]

Alice Assinger (Vienna, Austria)

Liver Regeneration: the Role of Platelets and the Immune System

12:30-14:30

Poster Session and Lunch

14:30-15:30

Parallel Oral Communications

Brain Plasticity, Neurodegeneration and Functional Recovery     [Aula Magna]

Dmitry Lim (Novara, Italy)

A Chicken and the Egg: ER-Mitochondrial Interaction and Protein Homeostasis in Alzheimer’S Disease and Beyond.

Francesca Miraglia (Rome, Italy)

Early EEG Signatures and Motor Function Alteration as Novel Prognostic Markers of Alzheimer's Disease

Maria Vittoria Podda (Rome, Italy)

Combined Neuromodulatory and Anti-Inflammatory Strategies Promote Recovery after Stroke

Giulia Puliatti (Rome, Italy)

Fluorescence Lifetime Imaging Microscopy as a Translational Strategy for Alzheimer’S Disease Diagnosis

Dopaminergic Circuits and Neurovascular Physiology     [Auditorium A1]

Veronica Bonalume (Milan, Italy)

Endothelium Heterogeneity Confers Brain-Specific Sensitivity to Macrophage-Derived IGF1 During Developmental Angiogenesis and Aging

Cristina Roseti (Varese, Italy)

LRRK2 G2019S Impairs GABA_A Receptor-Mediated Inhibitory Signaling in the Striatum

Giorgia Ferniani (Cagliari, Italy)

D-Serine Restores Corticostriatal Synaptic Function and Improves Motor Performance in a Rat Model of Parkinson’s Disease

Darin Zerti (L'Aquila, Italy)

Unveiling a Novel GPR143-Mediated Intracellular Pathway Underlying L-DOPA Protective Effects on Retinal Pigment Epithelium Homeostasis in the Age-Related Dysfunctions

Gut-Brain Axis, Metabolism and Endocrine Function     [Auditorium B1]

Amilcare Barca (Lecce, Italy)

Functional Characterization of SLC15A4 (Peptide/histidine Transporter 1): pH Dependence, Nitrate Modulation, and Substrate Versatility

Pasquale Calvi (Palermo, Italy)

Gut Microbiota-Dependent Effects of Opuntia Ficus Indica Fruit in Obesity-Induced Brain Dysfunctions

Alessandra Galli (Milan, Italy)

Nuclear Mechanosensing as a Regulator of Human Pancreatic β‑Cell Physiology

Carla Perego (Milan, Italy)

The Peptide Transporter SLC15A4 as a Metabolic Gatekeeper of β-Cell Secretory Function

Gastrointestinal, Liver and Nutritional Physiology     [Auditorium C1]

Grazia Tamma (Bari, Italy)

A Functional Therapeutic Food Enriched with Hydrolyzed Buffalo Whey Promotes Intestinal Adaptive Responses during Nutritional Stress

Elisabetta Piva (Padua, Italy)

POLAR-TOX: Assessing Bisphenol A-Induced Oxidative Stress and Gut Microbiota Responses in The Antarctic Fish Trematomus bernacchii

Alperen Akbaba (Istanbul, Turkey)

Meteorin-Like Protein (METRNL/IL-41) Alleviates Irritable Bowel Syndrome by Regulating Visceral Sensitivity, Motility and Leukocyte Trafficking in Rat Colon

Giuseppe Calamita (Bari, Italy)

Liver-Directed AAV-Mediated Gene Therapy Restores Lysosomal Acid Lipase Activity and Corrects the Disease Dysfunctions of a Murine Model of Wolman Disease

15:30-17:00

Parallel Symposia

The interplay of synaptic plasticity and oscillations in the cerebellar circuit     [Aula Magna]
Chair: Francesca Prestori (Pavia, Italy)

Annibale Antonioni (Ferrara, Italy)

Combined Cerebellar Theta-tACS+iTBS Enhances Corticospinal Excitability and Motor Performance in Healthy Subjects and in Patients with Chronic Stroke

Daniela Popa (Paris, France)

Cerebellum in Defensive Behaviors

Eleonora Pali (Pavia, Italy)

Dendritic Processing Integrates STDP on the Theta Band in Cerebellar Golgi Cells

Lucas Rudelt (Göttingen, Germany)

Dendritic Predictive Learning in Cerebellum-Like Circuits

Blood-brain barrier permeability in health and disease: mechanisms and modulation     [Auditorium A1]
Chairs: Valentina Castagnola (Pisa, Italy) & Luca Maragliano (Ancona, Italy)

Giuseppe Battaglia (Barcelona, Spain)

Macromolecular Transport at the Blood-Brain Barrier: Mechanisms, Dysfunctions, and Therapeutic Opportunities

Matthew Campbell (Dublin, Ireland)

Regulation of Claudin-5 at the Blood-Brain Barrier in Health and Disease

Martina Trevisani (Helsinki, Finland)

Targeting Tight Junctions: Blood-Brain Barrier Modulation Through Claudin-5-Binding Peptides

Arianna Benedetti (Genoa, Italy)

Oxytocin Seals the Blood-Brain Barrier, Improving 22q11.2 Deletion Syndrome Trajectories

Novelty in phosphate homeostasis
(Sponsored by the French Society of Physiology and Integrative Biology, SPBI)     [Auditorium B1]
Chairs: Sandrine Lemoine (Lyon, France) & Emmanuel Letavernier (Paris, France)

Sandrine Lemoine (Lyon, France)

Renal Phenotype in X Linked Ricket Patients

Guillaume Courbon (Saint Etienne, France)

The Hormone FGF23 Acts as a Paracrine Inhibitor of Erythropoiesis in Iron Deficiency Anemia and Chronic Kidney Disease

Paola Ciceri (Milan, Italy)

Phosphate-Induced Endothelial Calcification: Cellular and Molecular Mechanisms

Caroline Halimi (Paris, France)

Differential Calcium-Sensing Receptor Sensitivity in Primary Hyperparathyroidism?

Physiology for space: what can we learn from animal and human models     [Auditorium C1]
Chairs: Matteo Cerri (Bologna, Italy) & Arianna Mazzoli (Naples, Italy)

Arianna Mazzoli (Naples, Italy)

Metabolic Health and Probiotic Modulation: Insights from Animal Models 

Marco Narici (Padua, Italy)

Neuromuscular Impairment in Simulated Hypogravity 

Emiliana Piscitiello (Darmstadt, Germany)

How Hypometabolism May Protect Astronauts from Radiation and Cancer

Maksymilian Aleksander Brzezicki (Oxford, United Kingdom)

Central Nervous System Adaptation to Spaceflight: Mechanisms of Plasticity and Neurophysiological Monitoring

17:00-17:30

Coffee break

17:30-18:30

SIF Ruzzier Lecture     [Aula Magna]

Egidio D'Angelo (Pavia, Italy)

Multiscale Brain Models and Digital Twins

19:00-20:00

Special City Council Event      [Auditorio San Barnaba] (open, free)

08:30-10:00

Parallel Symposia

Beyond small cohorts: from extreme and space physiology to integrated, tailored human research (Sponsored by Experimental Physiology)     [Aula Magna]
Chair: Irene Di Giulio (London, United Kingdom)

Alexander Stahn (Berlin, Germany)

From Spaceflight to Antarctica: Environmental Extremes as Drivers of Human Brain Plasticity

Antoine Collet (Mons, Belgium)

Cardiovascular Adaptations to Microgravity and Advanced Cardiovascular Monitoring Technologies

Siobhan Crosby (Southampton, United Kingdom)

Exploring the Complexities of Adaptation to Extreme Environments Through Integrated Phenotyping Analysis

Dominik Pesta (Cologne, Germany)

Why Muscle Fails without Load: Translational Insights from Bed Rest to Metabolic Disease

Adaptive mechanisms and metabolic changes of non-neuronal cells in the central and peripheral nervous system     [Auditorium A1]
Chair: Nina Vardjan (Ljubljana, Slovenia)

Nicole Scholz (Leipzig, Germany)

Split Decisions at Neuroglial Junctions: How Adhesion GPCRs Shape Cell Interactions

Nunzio Vicario (Catania, Italy)

Neuroglial Intercellular Communication and Redox Dysregulation in Chronic Neuropathic Pain

Nina Vardjan (Ljubljana, Slovenia)

Reversing Age-Related Motor Decline Through Neuromodulatory Calcium Signals

Valerio Magnaghi (Milan, Italy)

Shaping the Inflammatory Cells in Schwann Cell-Related Tumors of the Peripheral Nervous System 

Modeling human neurodevelopment: 2D and 3D systems in physiological and pathophysiological conditions     [Auditorium B1]
Chairs: Bruno Sterlini (Genoa, Italy) & Bernadette Basilico (Rome, Italy)

Nael Nadif Kasri (Nijmegen, The Netherlands)

Multimodal Mapping of Neuronal Network Activity and Transcriptomic Identifies Convergent and Divergent Neurons in Neurodevelopmental Disorders

Orly Reiner (Rehovot, Israel)

LIS1, a Regulator of Brain Homeostasis

Caterina Sanchini (Rome, Italy)

Microfluidic 3D Bioprinting of a Human Neurovascular Model for CNS Drug Screening and Kabuki Syndrome Modeling

Bernadette Basilico (Rome, Italy)

Dissecting Patient-Specific Mechanisms in SYNGAP1 Syndrome Using Human in vitro Models

Environmental and molecular stressors regulating placental function and feto–maternal communication     [Auditorium C1]
Chairs: Leonardo Ermini (Siena, Italy) & Marco Fiocchetti (Rome, Italy)

Jorge Lopez Tello (Madrid, Spain)

Placental Hormones and Bacteria: Partners in Crime in the Regulation of Fetal Growth

Elisa Magistrati (Basel, Switzerland)

Decoding How Maternal Signals Regulate Trophoblast Invasion During Human Placental Development Using a High-Content Imaging Screen

Leonardo Ermini (Siena, Italy)

Placental Extracellular Vesicles as Mediators of Materno–Fetal Signaling in Health and Disease

Beatrice Tranquilli (Rome, Italy)

Modulation of Maternal-Fetal Interface: in vitro Evidence of Pollutant-Driven Changes in Placental-Neuron Communication

10:00-11:00

Parallel Oral Communications

Exercise Physiology and Metabolic Adaptation     [Aula Magna]

Raquel Cano García (Sevilla, Spain)

Impact of 16:8 Intermittent Fasting on Bioelectrical Phase Angle and Aerobic Performance in Active Young Adults

Elif Akın (Istanbul, Turkey)

Effects of Tirzepatide Treatment on Muscle, Cognitive Functions and Behavioral Outcomes in Rats With Obesity: Role of Resistance Exercise and WHEY Protein Supplementation

Nerijus Eimantas (Kaunas, Lithuania)

Effects of a 48-Hour Fast on Resting Metabolism, Exercise Performance and Recovery in Female Endurance Athletes

Beatrice Maspes (Brescia, Italy)

Respiratory Kinetics in Eccentric and Concentric Cycling

Glial Physiology in Brain Development and Neuroinflammation     [Auditorium A1]

Simona D'Aprile (Enna, Italy)

Connexin Network Remodeling Drives Maladaptive Astrocyte–Microglia Responses in Chronic Neuroinflammation

Eleonora De Santis (Rome, Italy)

Dystrophin Contributes Through Multiple Mechanisms to Microglial Homeostasis and Motor Neuron Health in the Mouse Lumbar Spinal Cord

Simone Diana (Moncalieri, Italy)

Investigation of Emerging Electrical Properties in Glia-Enriched Cerebellar Organoids

Enrica Boda (Orbassano, TO, Italy)

A Glial Origin of Cortical Network Dysfunction: Hypomyelination Drives Connectivity Defects, Hyperexcitability, and Cognitive Impairment in Oligodendroglial Cit-k Mutants

Cellular Responses to Hypoxia in the Nervous System     [Auditorium B1]

Maria Amalia Di Castro (Rome, Italy)

Targeting Microglia Counteracts Neuronal Hyperexcitability in Glioblastoma

Maria Vittoria Leonardi (Perugia, Italy)

Moderate Hypoxia Enhances Glioblastoma Invasiveness via Ion Channel Upregulation

Michele Maffia (Lecce, Italy)

Modulation of the Autophagic Process by S1P Under Hypoxia: Dissecting the Role of S1P1 and S1P5 Receptors in Neuronal Cell Model

Filippo Torrisi (Catania, Italy)

Metabolic and Redox Reprogramming in IDH1-Mutant Glioma Under Hypoxic Conditions

Epithelial Transport and Cellular Bioelectricity     [Auditorium C1]

Francesco Lodola (Milan, Italy)

Light-Driven Termination of Cardiac Reentry by a Membrane-Targeted Photoswitch

Silvia Dossena (Salzburg, Austria)

The Novel ZBTB16/CUL3/ROC1 Ubiquitin Ligase Regulates the Epithelial Anion Exchanger Pendrin (SLC26A4)

Simona Martinotti (Alessandria, Italy)

Modulation of AQP1 Expression and Calcium Dynamics by Umbilical Cord PRP in Corneal Wound Healing

Maira Certini (Bari, Italy)

Reversing Time: OSKM-Mediated Rejuvenation Enhances Lifespan and Healthspan in Drosophila melanogaster

11:00-11:30

Coffee break

11:30-12:30

SIF Lecture     [Aula Magna]

Silvano Sozzani (Rome, Italy)

Defining the Boundary between Immune System Physiology and Pathology

12:30-14:30

Poster Session and Lunch

14:30-15:30

Parallel Oral Communications

Renal and Calcium-Sensing Cell Physiology     [Aula Magna]

Marianna Ranieri (Bari, Italy)

Calcium-Sensing Receptor–β-Integrins Interaction as Novel Molecular Mechanism in Endometrial Receptivity

Mariangela Centrone (Bari, Italy)

Simulated Microgravity Impairs Renal Fluid Homeostasis via AMPK-Mediated AQP2 Downregulation and Mitochondrial Dysfunction in Collecting Duct Cells

Andrea Gerbino (Bari, Italy)

P2X7 Receptor Activation Drives Sustained Membrane Hyperpolarization and Reduces Migration in Clear Cell Renal Cell Carcinoma Cells

Simona Scorza (Bari, Italy)

The Lysosomal Calcium Channel TRPML1 Tunes the Autophagic Response to Fluid Shear Stress in Collecting Duct Cells

Neuronal Excitability and Network Dysfunction     [Auditorium A1]

Anna Corradi (Genoa, Italy)

Role of TMEM151A in Neuronal Development and in Paroxysmal Disorders

Giuditta Gambino (Palermo, Italy)

Longitudinal Behavioral and Electrophysiological Signatures of Network Dysfunction in a Temporal Lobe Epilepsy Rat Model: From Epileptogenesis to Drug Resistance

Alessandra Lodi (Orbassano, TO, Italy)

The GluN2A(N615S) Mutation as a Physiological Determinant of Sex-Dependent Audiogenic Seizure Susceptibility and Ketogenic Diet Response 

Qianwen Zhang (Pavia, Italy)

Altered Cerebellar Network Dynamics and Purkinje Cell Excitability in a PV-Pcdh19 Mouse Model of Developmental and Epileptic Encephalopathy-9

Skeletal Muscle Plasticity Across Health, Aging and Disease     [Auditorium B1]

Sira Karvinen (Jyväskylä, Finland)

Skeletal Muscle Senescence in Rats: Contributions of Genetic Aerobic Capacity, Aging, and Exercise

Lucia Acampora (Naples, Italy)

Voltage-Gated Potassium Channels Mediate Thyroid Hormone Control of Skeletal Muscle Excitability

Maira Rossi (Pavia, Italy)

Single-Nucleus Transcriptomics Identifies Myonuclear Remodeling and Altered Intercellular Signaling During Human Disuse Atrophy

Chiara Felles (Pavia, Italy)

Skeletal Muscle Morphometric Changes Contribute to the Age-Related Decline in V̇O_2peak

Neural Circuits Underlying Perception, Action and Social Behaviour     [Auditorium C1]

Annalisa Bosco (Bologna, Italy)

Oculomotor Dynamics Reveal Latent Internal States During the Perception–Action Transition

Chang Hui Lin (Camerino, Italy)

Contrastive Learning Reveals Distinct Temporal Timescales for Task Execution and Adaptation in Robot-Assisted Reaching 

Giovanni Mirabella (Brescia, Italy)

Task Relevance Determines Whether Facial Emotion Valence Shapes Behavior

Marco Rinaudo (Rome, Italy)

Ventral Striatal Neuroimmune Signalling Regulates the Expression of Social Memory in Male C57BL/6 Mice

15:30-17:00

Parallel Symposia

Teaching Physiology in medical schools (Sponsored by the University of Brescia)     [Aula Magna]
Chair: Skadi Spindler (Amsterdam, The Netherlands)

Mathieu Nendaz (Genève, Switzerland)

Integrating Physiology Teaching in a Problem-Based Learning Curriculum of Medical Training

Dario Torre (Turin, Italy)

Innovations in Physiology Teaching and Assessment in the Italian Medical Education System

Fiorenzo Conti (Ancona, Italy)

What, if Anything, Is a Textbook of Physiology in the Digital Era (and How to Make It)

Skadi Spindler (Amsterdam, The Netherlands)

Enhancing Clinical Reasoning in Physiology Through Branching-Scenario Films

Multiscale modelling of brain dynamics: toward brain digital twins     [Auditorium A1]
Chairs: Fulvia Palesi (Pavia, Italy) & Claudia Casellato (Pavia, Italy)

Jan Paul Triebkorn (Marseille, France)

The Virtual (Mouse) Brain as an Instrument for Understanding Physiopathological Brain Dynamics 

Jonathan Mapelli (Modena, Italy)

Integrating Cellular Level Models Into Whole Brain Simulators 

Marialaura De Grazia (Pavia, Italy)

From Cerebellar Spiking Circuit Pathophysiology to Virtual Mouse Brain Dynamics

Claudia Angela Michela Gandini Wheeler-Kingshott (London, United Kingdom)

The Role of the Cerebellum in Brain Digital Twins

Multimodal Structural and Biochemical Dissection of Striated Muscle Regulation     [Auditorium B1]
Chairs: Bert Blaauw (Padua, Italy) & Luca Fusi (London, United Kingdom)

Luca Fusi (London, United Kingdom)

Sub-Sarcomeric Regulation of Thin and Thick Filaments in Myofibrils Isolated from Striated Muscle

Ilaria Morotti (Florence, Italy)

Dual Filament Regulation of Cardiac Output Investigated with X-Ray Diffraction

Leonardo Nogara (Padua, Italy)

The Thin Line between Biochemistry and Structure where Myosin Super Relaxed State Lies

Leonardo Sacconi (Florence, Italy)

Probing Relaxed Myosin States in Hypertrophic Cardiomyopathy by Second Harmonic-Generation Microscopy

Prediction and action control in adaptive behavior: a multilevel framework in a distributed network     [Auditorium C1]
Chairs: Pierpaolo Pani (Rome, Italy) & Yuki Kikuchi (Newcastle Upon Tyne, United Kingdom)

Valentina Giuffrida (Newcastle Upon Tyne, United Kingdom)

Neural Representations of Predictive Information Processing and Adaptive Motor Control

Md. Tanbeer Haque (Rome, Italy)

Salience and Attentional Modulation of Response Control

Silvia Picazio (Rome, Italy)

Cerebellar Contribution to Inhibitory Control of Action and Thought. Insights from Patients and Healthy Participants Investigated Through Non-Invasive Brain Stimulation

Gioele Gavazzi (Florence, Italy)

From Proactive to Reactive Control: Prefrontal Functional Gradients as a Function of Inhibitory Demand

17:00-17:30

Coffee break

17:30-18:30

FEPS Lecture     [Aula Magna]

Pieter Roelfsema (Amsterdam, The Netherlands)

Visual Perception, Visual Consciousness and Restoring It in Blindness

19:45-20:30

Dinner speech and aperitif     [Museo Auto Storiche Brescia]

Luca Zampaglione (Tallinn, Estonia)

How Cyber Security Can Be Dealt in Multinational Critical Infrastructures

20:30

Social dinner     [Museo Auto Storiche Brescia]

08:30-10:00

Parallel Symposia

Novel approaches to understanding renal function using cutting edge metabolomics     [Aula Magna]
Chairs: Oleg Palygin (Charleston, SC, USA) & Arianna Carolina Rosa (Turin, Italy)

Markus Rinschen (Aarhus, Denmark)

Novel Approaches to Study Metabolic Communication of the Kidney

Jeremy Prokop (Grand Rapids, MI, USA)

Finding Convergence in the Data and Omics of Renal Genetics

Christine Klemens (Tampa, FL, USA)

Metabolic Insights Into Pathogenesis of Polycystic Kidney Disease from Cyst Fluid Composition

Daria Ilatovskaya (Augusta, GA, USA)

Sex Differences in Human Renal Metabolomics

A journey through the sensory system: from physiology to dysregulation in neurodevelopmental disorders     [Auditorium A1]
Chairs: Caterina Michetti (Genoa, Italy) & Leena E Williams (Edinburgh, United Kingdom)

Kengo Takahashi (Amsterdam, The Netherlands)

Feeling the Void: Inactivation-Mediated Investigation of the Neuronal Mechanisms of Visual Perception

Georgina Mills (London, United Kingdom)

Sensory Dysfunction in Epileptic Encephalopathies

Leena E Williams (Edinburgh, United Kingdom)

Sense and Sensibility in Fragile X Syndrome

Lorenzo Ciano (Genoa, Italy)

Social Deficits Parallel Sensory Alterations in a Mouse Model of Behavioral Regression

From abysses to space: how the human body copes with environmental stress     [Auditorium B1]
Chairs: Carlo Capelli (Milan, Italy) & Alex Buoite Stella (Trieste, Italy)

Antonis Elia (Stockholm, Sweden)

Breath-Holding: Human Physiological Plasticity Under Oxygen Limitation

Paola Zamparo (Verona, Italy)

Environmental Stress at the Water Surface

Giovanni Vinetti (Bolzano, Italy)

Raising the Ceiling in High Altitude Adaptation

Riccardo Sorrentino (Ljubljana, Slovenia)

From Deconditioning to Prevention: Physiological Challenges of Microgravity and Countermeasure Development

The molecular architecture of the epileptic brain: new pathophysiological insights     [Auditorium C1]
Chair: Mattia Lorenzo DiFrancesco (Genoa, Italy)

Massimo Mantegazza (Valbonne-Sophia Antipolis, Nice, France)

Mechanisms of SCN1A/NaV1.1 Sodium Channel Dysfunctions in Epilepsy: Dravet Syndrome and Beyond

Amanda Almacellas Barbanoj (London, United Kingdom)

Malformations of Cortical Development, Epilepsy and Co-Morbidities

Annamaria Vezzani (Milan, Italy)

Cellular and Molecular Inflammatory Mechanisms Involved in the Development of Epilepsy and Pharmacoresistance

Alberto Sánchez-Aguilera López (Madrid, Spain)

Hippocampal and Cortical Rhythmpathies in Experimental Models of Brain Metastasis

10:00-11:00

Awards Ceremony

10:00-10:20 • FEPS Rising Star Award

Marcin Magierowski (Krakow, Poland)

Sulfide signaling imbalance in gastrointestinal pathophysiology

10:20-10:40 • SIF Prizes

10:40-11:00 • YRP and FEPS Travel Awards

11:00-11:30

Coffee break

11:30-12:30

SIF Herlitzka Lecture     [Aula Magna]

Carlo Reggiani (Padua, Italy)

In the World of Skeletal Muscle Fibers: New Insights from Omics Investigations

12:30-14:30

Poster Session and Lunch

14:30-15:30

pH Lecture      [Aula Magna]

Hannah Monyer (Heidelberg, Germany)

Space Cognition, from Kant to Contemporary Neuroscience

15:30-18:30

SIF Assembly